| Locality | Post Code |
|---|---|
| Altamont, Effingham | 62411 |
| Beecher City, Effingham | 62414 |
| Blue Point, Effingham | 62401 |
| Boggsville, Effingham | 62401 |
| Dieterich, Effingham | 62424 |
| Douglas, Effingham | 62401 |
| Edgewood, Effingham | 62426 |
| Effingham, Effingham | 62401 |
| Funkhouser, Effingham | 62401 |
| Gila, Effingham | 62445 |
| Gilmore, Effingham | 62443 |
| Green Creek, Effingham | 62401 |
| Heartville, Effingham | 62401 |
| Island Grove, Effingham | 62467 |
| Laclede, Effingham | 62426 |
| Lake Sara, Effingham | 62401 |
| Larkinsburg, Effingham | 62426 |
| Lillyville, Effingham | 62401 |
| Mason, Effingham | 62443 |
| Montrose, Effingham | 62445 |
| Northmore Heights, Effingham | 62401 |
| Park Hills, Effingham | 62401 |
| Saint Francis, Effingham | 62467 |
| Saint Marys, Effingham | 62401 |
| Shumway, Effingham | 62461 |
| Teutopolis, Effingham | 62467 |