| Locality | Post Code |
|---|---|
| Cateechee, Pickens | 29667 |
| Central, Pickens | 29630 |
| Clemson, Pickens | 29631, 29632, 29634 |
| Cleveland, Pickens | 29635 |
| Easley, Pickens | 29640, 29642 |
| Liberty, Pickens | 29657 |
| Norris, Pickens | 29667 |
| Pickens, Pickens | 29671 |
| Powdersville, Pickens | 29642 |
| Six Mile, Pickens | 29682 |
| Sunset, Pickens | 29685 |